Insights & Updates

Financial Wisdom for the Plant Medicine Frontier

Expert tax strategies, regulatory news, and financial best practices tailored for cannabis and psychedelic business leaders.

Rescheduling, 280E, and the Fight for Retrospective Relief

The Attorney General's final order partially rescheduling marijuana has left the cannabis community with many lingering questions around 280E: when relief is effective, who qualifies, and what taxpayers can do while waiting for guidance.
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Prioritizing Tax Payments When Cash Is Tight

When funds are limited, the way a taxpayer prioritizes tax obligations can affect assessed penalties, interest, and enforcement risk. Not all taxes are treated the same, and understanding that hierarchy is the starting point.
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"The Single Convention Angle” to “A New Choke Point”

The DEA has placed state licensed medical marijuana into Schedule III effective April 22, 2026, ending Section 280E for qualifying businesses. But recreational cannabis rescheduling remains in a separate process. Here is what it means for cannabis operators.
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A Closer Look at IRC 280E (And Where We Stand)

A taxpayer is entitled to challenge the IRS’s interpretation of the law, including positions related to IRC § 280E. In fact, there are mechanisms built into the tax code and specified tax forms to facilitate this.
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The Dormant Commerce Clause and the Future of Cannabis Markets

On August 12, 2025, the U.S. Court of Appeals for the Second Circuit issued a key ruling in Variscite NY Four, LLC v. New York State Cannabis Control, with major implications for how interstate commerce affects state cannabis markets.
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Michigan’s 24% Wholesale Cannabis Tax Will Force Consolidation

Michigan lawmakers are proposing a 24% wholesale excise tax on cannabis transfers, adding to current retail taxes. Though expected to raise $420 million for infrastructure, it may drive consolidation, disadvantaging small operators in favor of large firms.
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DEA Forwards Psilocybin Rescheduling Petition to the HHS: What This Means for the Industry

The DEA has sent a petition to reschedule psilocybin from Schedule I to II, prompting HHS review. This could reshape business regulations, tax implications under IRS 280E, and the future of the psychedelics industry.
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Can magic mushroom companies successfully challenge 280E?

A detailed legal and policy analysis of IRS Code § 280E, its impact on cannabis and psilocybin industries, and the argument that psilocybin
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Challenging 280E: Why “Within the Meaning” Matters

Internal Revenue Code Section 280E is beginning to resemble a dried and brittle leaf, clinging to the branch of antiquated federal law long after the season
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Challenging 280E: HHS’s Authority and the Collapse of Drug Scheduling Powers

The cannabis and psychedelics industries are currently subject to one of the most punitive tax codes in the U.S. Internal Revenue Code § 280E, which...
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The Fight Over Cannabis Rescheduling: Progress, Setbacks, and the Battle Ahead

For decades, the Drug Enforcement Administration (DEA) has relied on a rigid five-part test to determine whether a drug has a “currently accepted medical...
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Justin to be speaking at MJBizCon Dec 3-6.

The Future of Cannabis Investment in a Post-280E Landscape We’re thrilled to announce that Calyx CPA’s own CEO, Justin Botillier, will be speaking at MJBizCon
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